Mutant enzyme study aids in understanding of sirtuin’s functions

ITHACA, N.Y. – The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood. A team of Cornell University researchers, led by Hening Lin, professor of chemistry and chemical biology, has devised […]