Mutant enzyme study aids in understanding of sirtuin’s functions

ITHACA, N.Y. – The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood. A team of Cornell University researchers, led by Hening Lin, professor of chemistry and chemical biology, has devised […]

Cornell-Swiss study finds protein with power to improve heart function

ITHACA, N.Y. – The human heart is a remarkable muscle, beating more than 2 billion times over the average life span. But the heart’s efficiency can decrease over time. One major contributor to this decreased function is cardiac hypertrophy – a thickening of the heart muscle, resulting in a decrease in the size of the […]